Abstract
1-Methoxycarbonylaziridines react under mild conditions with a number of nucleophilic reagents such as water, acids, alcohols, and amines with opening of the aziridine ring. In the case of 7-methoxycarbonyl-7-azabicyclo[4.1.0]heptane it was shown by PMR spectroscopy that the ring-opening reaction is realized stereoselectively to give trans-1,2-disubstituted cyclohexanes.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1054–1057, August, 1981.
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Baranov, S.V., Mochalin, V.B. Reactions of 1-alkoxycarbonylaziridines with nucleophilic reagents. Chem Heterocycl Compd 17, 779–782 (1981). https://doi.org/10.1007/BF00503657
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DOI: https://doi.org/10.1007/BF00503657