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Synthesis of 1-alkyl-4(5)-hydroxymethyl-1,2,3-triazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

An in situ method for the synthesis of 1-alkyl-4(5)-hydroxymethyl-1,2,3-triazoles by the action of acetylenic alcohols with alkyl azides as the latter are formed from sodium azide and alkyl halides in dimethylformamide is proposed.

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Literature cited

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1688–1689, December, 1980.

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Maksikova, A.V., Serebryakova, E.S., Tikhonova, L.G. et al. Synthesis of 1-alkyl-4(5)-hydroxymethyl-1,2,3-triazoles. Chem Heterocycl Compd 16, 1284–1285 (1980). https://doi.org/10.1007/BF00501836

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  • DOI: https://doi.org/10.1007/BF00501836

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