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Synthesis and study of 3-(pyrimidin-2-yl)amino-1(2)H-1,2,4-triazole derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The previously unknown 3-[4(3H)-pyrimidinon-2-yl]amino-1H-1,2,4-triazoles, which were converted to 3-[4-chloro-, 3-(4-ethoxy)-, 3-(4-hydrazinopyrimidin-2-yl)]-amino-2(4)H-1,2,4-triazoles, were obtained by the reaction of 2-nitroamino-4(3H)-pyrimidinones with 3-amino-5-hexyl-1H-1,2,4-triazole. The condensation of the initial products with β-diketones gave 3-[4-(1H-pyrazol-1-yl)pyrimidin-2-yl]-amino-2(4)H-1,2,4-triazoles. The IR, UV, and PMR spectra of the synthesized compounds were studied.

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Literature cited

  1. A. V. Ivashchenko, O. N. Garicheva, L. V. Shmelev, Yu. S. Ryabokobylko, and G. M. Adamova, Khim. Geterotsikl. Soedin., No. 12, 1673 (1980).

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Authors and Affiliations

  1. All-Union Scientific-Research Institute of Chemical Reagents and Ultrapure Chemical Substances, 107258, Moscow

    A. V. Ivashchenko, O. N. Garicheva, L. V. Shmelev, Yu. S. Ryabokobylko & G. M. Adamova

  2. Scientific-Research Institute of Organic Intermediates and Dyes, 103787, Moscow

    A. V. Ivashchenko, O. N. Garicheva, L. V. Shmelev, Yu. S. Ryabokobylko & G. M. Adamova

Authors
  1. A. V. Ivashchenko
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  2. O. N. Garicheva
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  3. L. V. Shmelev
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  4. Yu. S. Ryabokobylko
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  5. G. M. Adamova
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1678–1681, December, 1980.

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Ivashchenko, A.V., Garicheva, O.N., Shmelev, L.V. et al. Synthesis and study of 3-(pyrimidin-2-yl)amino-1(2)H-1,2,4-triazole derivatives. Chem Heterocycl Compd 16, 1275–1278 (1980). https://doi.org/10.1007/BF00501834

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  • DOI: https://doi.org/10.1007/BF00501834

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