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Mannich reaction in a series of six-membered heterocyclic γ-ketones

VIII. Structures of the products of aminomethylation of 2,2-dimethyl-4-oxotetrahydropyran, 2,2-dimethyl-4-oxotetrahydrothiopyran, and 1,2,2-trimethyl-4-oxopiperidine

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Abstract

It was established by PMR spectroscopy and mass spectrometry that the aminomethylation of 2,2-dimethyl-substituted oxygen-, sulfur-, and nitrogen-containing six-membered cyclic γ- ketones gives the corresponding 5-aminomethyl derivatives.

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See [1] for communication VII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 903–906, July, 1975.

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Golovin, E.T., Glukhov, B.M., Botsman, L.S. et al. Mannich reaction in a series of six-membered heterocyclic γ-ketones. Chem Heterocycl Compd 11, 792–794 (1975). https://doi.org/10.1007/BF00497295

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  • DOI: https://doi.org/10.1007/BF00497295

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