Abstract
The nitration of 5-formyl- and 5-acetyl-2,2′-dithienyls by the action of potassium nitrate in 60–95% sulfuric acid solutions was studied. An increase in the acidity of the medium and a decrease in the reaction temperature from +30°C to −30°C lead to an increase in the percentage of the 5′-nitro isomer in the mixture.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1047–1050, August, 1977.
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Zimichev, A.V., Lipkin, A.E. & Safargalina, T.M. Effect op protonation of 2,2′-dithienyl carbonyl compounds on the direction of substitution during nitration. Chem Heterocycl Compd 13, 840–843 (1977). https://doi.org/10.1007/BF00488904
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DOI: https://doi.org/10.1007/BF00488904