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Chemistry of Heterocyclic Compounds

, Volume 26, Issue 5, pp 561–564 | Cite as

Pyrido[2,3-d]pyrimidines. 2. Reactions of 2,4,5-trioxo-7-amino-8H-pyrido[2,3-d]pyrimidines with electrophilic agents

  • O. A. Burova
  • I. D. Bystryakova
  • N. M. Smirnova
  • T. S. Safonova
Article
  • 44 Downloads

Abstract

1,3-Dimethyl-2,4,5-trioxo-7-amino-8H-pyrido[2,3-d]pyrimidine has been brominated, chlorosulfonated, treated with potassium nitrite in acidic medium, and with the Vilsmeier reagent. Acylation and alkylation of 1,3-dimethyl-2,4,5-trioxo-6-bromo-7-aminopyrido[2,3-d]pyrimidine is also discussed.

Keywords

Potassium Organic Chemistry Nitrite Pyrimidine Alkylation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature Cited

  1. 1.
    O. A. Burova, N. M. Smirnova, and T. S. Safonova, Khim. Geterotsikl. Soedin. (in press) (1990).Google Scholar
  2. 2.
    K. Hitota, Y. Kitade, H. Sajioki, and Y. Maki, Synthesis, No. 7, 589 (1984).Google Scholar

Copyright information

© Plenum Publishing Corporation 1990

Authors and Affiliations

  • O. A. Burova
    • 1
  • I. D. Bystryakova
    • 1
  • N. M. Smirnova
    • 1
  • T. S. Safonova
    • 1
  1. 1.Chemico-Pharmaceutical Sciences Research InstituteNovokuznetsk

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