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Pyrido[2,3-d]pyrimidines. 2. Reactions of 2,4,5-trioxo-7-amino-8H-pyrido[2,3-d]pyrimidines with electrophilic agents

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

1,3-Dimethyl-2,4,5-trioxo-7-amino-8H-pyrido[2,3-d]pyrimidine has been brominated, chlorosulfonated, treated with potassium nitrite in acidic medium, and with the Vilsmeier reagent. Acylation and alkylation of 1,3-dimethyl-2,4,5-trioxo-6-bromo-7-aminopyrido[2,3-d]pyrimidine is also discussed.

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Literature Cited

  1. O. A. Burova, N. M. Smirnova, and T. S. Safonova, Khim. Geterotsikl. Soedin. (in press) (1990).

  2. K. Hitota, Y. Kitade, H. Sajioki, and Y. Maki, Synthesis, No. 7, 589 (1984).

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For Communication 1, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 662–666, May, 1990.

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Burova, O.A., Bystryakova, I.D., Smirnova, N.M. et al. Pyrido[2,3-d]pyrimidines. 2. Reactions of 2,4,5-trioxo-7-amino-8H-pyrido[2,3-d]pyrimidines with electrophilic agents. Chem Heterocycl Compd 26, 561–564 (1990). https://doi.org/10.1007/BF00487434

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  • DOI: https://doi.org/10.1007/BF00487434

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