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Synthesis of pyrrole-2-carboxylic acids and their N-vinyl derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Haloform cleavage of 2-trifluoroacetyl- and N-vinyl-2-trifluoroacetylpyrroles gives pyrrole-2-carboxylic acids and their N-vinyl derivatives in good yields; most of these compounds do not melt between 120–190‡C, but rather decompose with CO2 evolution.

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Authors and Affiliations

  1. Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, Irkutsk

    L. N. Sobenina, M. P. Sergeeva, A. I. Mikhaleva, M. V. Sigalov, S. E. Korostova, N. I. Golovanova, V. N. Salaurov, E. V. Bakhareva & N. N. Vasil'eva

Authors
  1. L. N. Sobenina
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  2. M. P. Sergeeva
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  3. A. I. Mikhaleva
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  4. M. V. Sigalov
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  5. S. E. Korostova
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  6. N. I. Golovanova
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  7. V. N. Salaurov
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  8. E. V. Bakhareva
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  9. N. N. Vasil'eva
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 612–616, May, 1990.

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Sobenina, L.N., Sergeeva, M.P., Mikhaleva, A.I. et al. Synthesis of pyrrole-2-carboxylic acids and their N-vinyl derivatives. Chem Heterocycl Compd 26, 516–520 (1990). https://doi.org/10.1007/BF00487424

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  • DOI: https://doi.org/10.1007/BF00487424

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