Abstract
Spatial directivity of reactions of the geometrical isomers of 4-acetyl-, 4-propionyl-, and 4-benzoyl-1,2,5-trimethyl-4-piperidols with Grignard reagents and lithium aluminum hydride has been studied. Stereospecific synthesis of some stereoisomeric 4-hydroxy-1,2,5-trimethyl-4-piperidyl carbinols has been effected and their probable spatial configurations have been discussed.
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Unkovskii, B.V., Shulaev, N.P., Badosov, E.P. et al. Synthesis of 4-hydroxy-1,2,5-trimethyl-4-piperidyl carbinols. Chem Heterocycl Compd 4, 759–762 (1968). https://doi.org/10.1007/BF00486952
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DOI: https://doi.org/10.1007/BF00486952