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Synthesis of new pyrazole and isoxazole derivatives based on products of condensation of β-dicarbonyl compounds with 1,2,3-trihalopropanes

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 2-(2-halo-3-propenyl)-1,3-dicarbonyl compounds, which are formed in the alkylation of Β-dicarbonyl compounds with 1,2,3-trihalopropanes in the presence of potassium carbonate in DMSO, with hydrazine and hydroxylamine derivatives was studied. The synthesis of new pyrazole and isoxazole derivatives on the basis of this reaction is described. Some chemical transformations of the 1,2-azoles obtained were investigated.

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Authors and Affiliations

  1. S. M. Kirov Azerbaidzhan State University, 370073, Baku

    Sh. T. Akhmedov, N. S. Sadykhov, V. M. Ismailov, M. A. Akhundova, M. M. Mamedov, S. I. Kozhushkov & N. S. Zefirov

  2. M. V. Lomonosov Moscow State University, 117234, Moscow

    Sh. T. Akhmedov, N. S. Sadykhov, V. M. Ismailov, M. A. Akhundova, M. M. Mamedov, S. I. Kozhushkov & N. S. Zefirov

Authors
  1. Sh. T. Akhmedov
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  2. N. S. Sadykhov
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  3. V. M. Ismailov
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  4. M. A. Akhundova
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  5. M. M. Mamedov
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  6. S. I. Kozhushkov
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  7. N. S. Zefirov
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 787–791, June, 1987.

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Akhmedov, S.T., Sadykhov, N.S., Ismailov, V.M. et al. Synthesis of new pyrazole and isoxazole derivatives based on products of condensation of β-dicarbonyl compounds with 1,2,3-trihalopropanes. Chem Heterocycl Compd 23, 651–655 (1987). https://doi.org/10.1007/BF00486912

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  • DOI: https://doi.org/10.1007/BF00486912

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