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Chemistry of Heterocyclic Compounds

, Volume 4, Issue 4, pp 462–463 | Cite as

Syntheses of di- and tetrahydropyrroles

IV. Synthesis of substituted 4-isopropyl-2-methyl- and 2,4,4-trimethyl-δ1-pyrrolines
  • V. M. Berezovskii
  • V. B. Spiro
  • L. Ya. Denisova
  • B. M. Sheiman
Article
  • 26 Downloads

Abstract

By the Michael's condensation of 3-methyl-1-nitro-1-butene with esters of α-acetoglutaric and acetosuccinic acids and of 2-methyl-1-nitropropene with acetylacetone we have synthesized the corresponding γ-nitrocarbonyl compounds, which have been converted by reductive cyclization into 3-ethoxycarbonyl-4-isopropyl-3-methoxycarbonylethyl-2-methyl-Δ1-pyrroline, 3-ethoxycarbonyl-3-ethoxycarbonylmethyl-4-isopropyl-2-methyl-Δ1-pyrroline, and 3-acetyl-2, 4, 4-trimethyl-Δ1-pyrroline, respectively.

Keywords

Ester Organic Chemistry Acetylacetone Reductive Cyclization Tetrahydropyrroles 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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Copyright information

© Consultants Bureau 1971

Authors and Affiliations

  • V. M. Berezovskii
    • 1
  • V. B. Spiro
    • 1
  • L. Ya. Denisova
    • 1
  • B. M. Sheiman
    • 1
  1. 1.All-Union Scientific-Research Vitamin InstituteMoscow

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