Skip to main content
Log in

Nucleophilic substitution in hydroxyisoxazolidines

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Nucleophilic substitution of the hydroxy-group in 3- (or 5-)hydroxyisoxazolidines affords the aryl(alkyl)amino-, alkoxy-, and hydrazino-compounds. 5-Dimethylhydrazinooxazolidines exist preferentially in the linear form.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature Cited

  1. M. Ishidate, Y. Sakurai, and M. Torigae, Chem. Pharm. Bull., 19, 485 (1961).

    Google Scholar 

  2. P. Kulsa and C. Rooney, Ger. Offen. 2,100,242; Chem. Abstr., 75, 110,312 (1971).

    Google Scholar 

  3. G. Pifferi, Ger. Offen. 2,019,629; Chem. Abstr., 74, 22,819 (1971).

    Google Scholar 

  4. C. Challis and S. Webb, Ger. Offen. 2,639,189; Chem. Abstr., 87, 23,258 (1977).

    Google Scholar 

  5. P. De Shong, C. Dicken, R. Staib, A. Freyer, and S. Weinreb, J. Org. Chem., 47, 4397 (1982).

    Google Scholar 

  6. K. N. Zelenin, I. A. Motorina, L. A. Sviridova, I. P. Bezhan, A. Yu. Ershov, G. A. Golubeva, and Yu. G. Bundel', Khim. Geterotsikl. Soedin., No. 9, 1270 (1987).

    Google Scholar 

  7. K. N. Zelenin, A. V. Dovgilevich, I. P. Bezhan, G. A. Golubeva, L. A. Sviridova, L. V. Pastushenkov, é. G. Gromova, T. A. Gatchina, and S. V. Pomogaibo, Khim. Geterotsikl. Soedin., No. 5, 659 (1984).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1661–1665, December, 1988.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Motorina, I.A., Sviridova, L.A., Golubeva, G.A. et al. Nucleophilic substitution in hydroxyisoxazolidines. Chem Heterocycl Compd 24, 1373–1377 (1988). https://doi.org/10.1007/BF00486682

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00486682

Keywords

Navigation