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Reaction of tetrafluorodibenz[b,f][1,4]oxazepin-11(10H)-ones with nucleophiles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Reaction of 1,2,3,4-tetrafluorodibenz[b,f][1,4]oxazepin-11(10H)-one with nucleophilic reagents (MeONa in refluxing MeOH; piperidine in DMF at 100‡C) leads to substitution of the fluorine atom para to the CONH group. 6,7,8,9-Tetrafluorodibenz[b,f][1,4]oxazepin-11(10H)-one is inert to these conditions.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1259–1261, September, 1991.

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Konstantinova, A.V., Yakovleva, O.D. & Gerasimova, T.N. Reaction of tetrafluorodibenz[b,f][1,4]oxazepin-11(10H)-ones with nucleophiles. Chem Heterocycl Compd 27, 1016–1017 (1991). https://doi.org/10.1007/BF00484369

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  • DOI: https://doi.org/10.1007/BF00484369

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