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Production of alkane and cyclohexane derivatives with two heterocyclic substituents of the furan, pyrrole, and thiophene series

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Heating 1,2,11,12-tetrachloro-2,11-bis(R-4,9-dodecanediones) and 1,4-bis(3-R-3,4-dichlorobutanoyl)cyclohexanes gave, respectively, 1,4-difuryl derivatives of butane and cyclohexane, while treatment of them with primary amines or phosphorus pentasulfide in DMF was used to synthesize dipyrryl and dithienyl compounds. 1-R-3-R1-3,4-Dichlorobutanones react with ethylenediamine in aqueous alkali solutions to give 1,2-dipyrryl or monopyrryl derivatives of ethane.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1185–1189, September, 1991.

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Mamedov, É.I., Ismailov, A.G., Goyushov, R.D. et al. Production of alkane and cyclohexane derivatives with two heterocyclic substituents of the furan, pyrrole, and thiophene series. Chem Heterocycl Compd 27, 947–951 (1991). https://doi.org/10.1007/BF00484356

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  • DOI: https://doi.org/10.1007/BF00484356

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