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Indole derivatives

XXIII. Reduction of some polyalkylated tetrahydro-γ-carbolines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Reduction of 2,2,4-trimethyl-, 2,2,4,4,6-pentamethyl-, and 2,2, 4,4,9-pentamethyl-1,2,3,4-tetrahydro-γ-carboline gives 1,2,3,4, 4a,9a-hexahydro-γ-carbolines, along with products of destructive hydrogenation. The sole reduction product of 2,2,3,4,4-pentamethyl-1,2,3,4-tetrahydro-γ-carboline is 2-(β-methylaminoisobutyl)indoline.

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References

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Komzolova, N.N., Kucherova, N.F. & Zagorevskii, V.A. Indole derivatives. Chem Heterocycl Compd 3, 556–558 (1967). https://doi.org/10.1007/BF00481604

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  • DOI: https://doi.org/10.1007/BF00481604

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