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Mass spectrometry of biologically active substances

II. Mass spectra of barbituric acid derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The mass spectra of 2- and 4-iminobarbituric acid derivatives were studied in relation to the mass spectra of their oxygen analogs. It is shown that the pathways of fragmentation of the investigated compounds depend on the type of substituent attached to the C5 atom, the position of the imino and oxo groups in the ring, and the specific mass-spectral properties. The fragmentation was studied by means of low-voltage mass spectrometry and deuterium labeling.

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Literature cited

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Authors and Affiliations

  1. Branch of the S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, 142450, Kupavna, Moscow Oblast

    V. G. Voronin, A. I. Ermakov, N. K. Paramonov, Yu. N. Portnov & S. B. Goncharenko

Authors
  1. V. G. Voronin
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  2. A. I. Ermakov
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  3. N. K. Paramonov
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  4. Yu. N. Portnov
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  5. S. B. Goncharenko
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Additional information

See [1] for communication I.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 813–817, June, 1978.

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Voronin, V.G., Ermakov, A.I., Paramonov, N.K. et al. Mass spectrometry of biologically active substances. Chem Heterocycl Compd 14, 667–671 (1978). https://doi.org/10.1007/BF00481144

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  • DOI: https://doi.org/10.1007/BF00481144

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