Abstract
Methods of synthesis of 3-amino-4-ethoxycarbonylaminotetrahydrothiophene (VIII), and of other diamines, from 4-ethoxycarbonylaminotetrahydro-3-hydroxyiminothiophene (I), 2-benzylidene-4-ethoxycarbonylaminotetrahydro-3-hydroxyiminothiophene (III) and 4-ethoxycarbonylaminotetrahydro-3-hydroxythiophene (V) were investigated. Chlorination of V followed by the Gabriel synthesis gave VIII.
Similar content being viewed by others
References
S. D. Mikhno, T. P. Polyanskaya, and V. M. Berezovskii, KhGS [Chemistry of Heterocyclic Compounds] (in press).
L. C. Cheney and I. R. Piening, J. Am. Chem. Soc., 67, 729, 1945.
L. C. Karrer and Kehrer, Helv. Chim. Acta, 27, 142, 1944.
L. C. Cheney and I. R. Piening, J. Am. Chem. Soc., 66, 1040, 1944.
S. Harris, D. Wolf, K. Mozingo, C. Anderson, G. Arth, N. Easton, D. Heyl, A. Wilson, and K. Folkers, J. Am. Chem. Soc., 66, 1756, 1944.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mikhno, S.D., Polyanskaya, T.N. & Berezovskii, V.M. An investigation of the synthesis of 3-amino-4-ethoxycarbonylaminotetrahydrothiophene. Chem Heterocycl Compd 4, 569–570 (1971). https://doi.org/10.1007/BF00481017
Issue Date:
DOI: https://doi.org/10.1007/BF00481017