Abstract
It is shown that it is possible to use heterocyclic ketones to synthesize condensed pyrimidine derivatives in the case of 1-(p-toluenesulfo)-1,2,3,4-tetrahydroquinol-4-one, which on reaction with benzylidenebisurea gives 2-hydroxy-4-phenyl-6-(p-toluenesulfo)-3, 4, 5, 6-tetrahydropyrimido [5,4-c] quinoline, and the latter, after dehydrogenation via the 2-hydroxy, 2-chloro derivatives, was converted to 4-phenylpyrimido [5, 4-c] quinoline, a new heterocyclic system.
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References
Yu. P. Shvachkin, Usp. khim., 24, 824, 1957.
V. P. Mamaev, ZhOKh, in: Biologically active compounds [in Russian], 38, 1965.
V. P. Mamaev and V. F. Sedova, ZhOKh, in: Biologically Active Compounds [in Russian], 32, 1965.
L. J. Bellamy, The Infra-Red Spectra of Complex Molecules [Russian translation], IL, Moscow, 1963.
N. V. Khromov-Borisov and A. M. Savchenko, ZhOKh, 22, 1680, 1952.
K. Folkers and T. Johnson, J. Am. Chem. Soc., 55, 2886, 1933.
R. Schreiber, J. Am. Chem. Soc., 56, 1618, 1934.
Advances in Organic Chemistry [in Russian], 2, Mir, Moscow, 328, 1964.
G. W. Cooke and J. Gulland, J. Chem. Soc., 872, 1939.
P. J. Ittyerach and F. G. Mann, J. Chem. Soc., 467, 1958.
B. Lythgoe and L. Rayner, J. Chem. Soc., 2323, 1951.
W. S. Johnson, E. Woroch, and B. Buell. J. Am. Chem. Soc., 71, 1901, 1949.
V. P. Mamaev and V. F. Sedova, KhGS [Chemistry of Heterocyclic Compounds], 787, 1965.
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For Part IV see [13].
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Mamaev, V.P., Kim, A.M. Pyrimidines. Chem Heterocycl Compd 2, 189–193 (1967). https://doi.org/10.1007/BF00480968
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DOI: https://doi.org/10.1007/BF00480968