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Nucleophilic addition reactions of 3-ketothiophane derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Addition of hydroxylamine, ammonia and hydrocyanic acid to 4-benzoylamino-3-keto-2-(δ-carbomethoxybutylidene)-thiophane and to 4-benzoylamino-3-keto-2-benzylidenethiophane has been investigated. 4-Benzoylamino-3-keto-2-(δ-carbomethoxybutylidene) thiophane participates in a nucleophilic addition reaction both at the carbonyl group, and at the multiple bond, unlike 4-benzoylamino-3-keto-2-benzylidene-thiophane, which reacts only at the carbonyl group.

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Authors and Affiliations

  1. All-Union Scientific Research Institute for Vitamins, USSR

    S. D. Mikhno, N. S. Kulachkina & V. M. Berezovskii

Authors
  1. S. D. Mikhno
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  2. N. S. Kulachkina
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  3. V. M. Berezovskii
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Mikhno, S.D., Kulachkina, N.S. & Berezovskii, V.M. Nucleophilic addition reactions of 3-ketothiophane derivatives. Chem Heterocycl Compd 2, 125–127 (1967). https://doi.org/10.1007/BF00480953

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  • DOI: https://doi.org/10.1007/BF00480953

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