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Investigation of nitrogen- and sulfur-containing heterocycles

XXX. Reaction of 2-mercapto-3-ureido-6-chloropyridine with phenacyl halides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-Mercapto-3-ureido-6-chloropyridine reacts with the ortho, meta, and para derivatives of phenacyl halides to give 2-phenacylthio-3-ureido-6-chloropyridines, which are readily cyclized to 6-arylpyrido[2,3-b][1,4]thiazines regardless of the presence or absence of a substituent in the meta and para positions of the benzene ring.

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Literature cited

  1. N. V. Sazonov and T.S. Safonova, Khim. Geterotsikl. Soedin., 1694 (1973).

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See [1] for communication XXIX.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 798–800, June, 1974.

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Levkovskaya, L.G., Makeeva, V.V. & Safonova, T.S. Investigation of nitrogen- and sulfur-containing heterocycles. Chem Heterocycl Compd 10, 693–695 (1974). https://doi.org/10.1007/BF00480927

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  • DOI: https://doi.org/10.1007/BF00480927

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