Abstract
Intramolecular cyclization of 2-(N-acylselenoureido)-3-carbethoxy-4,5,6,7-tetrahydrobenzo[b]thiophenes in alkaline media leads to the formation of the potassium salt (I) of 2-seleno-4-oxo-3,4,5,6,7,8-hexahydrobenzo[b]thieno[2,3-d]pyrimidine, acidification of which yielded the corresponding base in free form. Some pyrimidine compounds containing a selenium atom in the side chain were obtained by reaction of potassium salt I with halo derivatives (ClCH2CH2COOCH3 and ClCH2CH2OH).
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
I. B. Douglas and F.B. Dains, J. Amer. Chem. Soc., 56, 719 (1934).
A. A. Dobosh, S. M. Khripak, and I. V. Smolanka, Khim. Geterotsikl. Soedin., No. 4, 486 (1974).
K. Gewald, Z. Chem., 2, 305 (1962).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 753–754, June, 1977.
Rights and permissions
About this article
Cite this article
Smolanka, I.V., Khripak, S.M., Zeikan', A.A. et al. Synthesis of 2-selenothieno[2,3-d]pyrimidine derivatives. Chem Heterocycl Compd 13, 609–610 (1977). https://doi.org/10.1007/BF00480662
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00480662