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Chemistry of Heterocyclic Compounds

, Volume 12, Issue 4, pp 437–439 | Cite as

Research on benzimidazole derivatives

XXXIX. Nucleophilic substitution in a series of 2-aryl- and 2-alkylbenzimidazole derivatives
  • I. I. Popov
  • Yu. G. Bogachev
  • P. V. Tkachenko
  • A. M. Simonov
  • B. A. Tertov
Article

Abstract

The corresponding 2-hydroxy- and 2-aminobenzimidazoles are formed when 1-methyl-2-phenyl-and 2-alkylbenzimidazoles are fused with potassium hydroxide or sodium amide. N-Dealkylation, dimerization of the benzimidazole derivatives, and cleavage of the heterocyclic ring accompany the principal trends of these transformations.

Keywords

Sodium Potassium Hydroxide Organic Chemistry Amide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1977

Authors and Affiliations

  • I. I. Popov
    • 1
  • Yu. G. Bogachev
    • 1
  • P. V. Tkachenko
    • 1
  • A. M. Simonov
    • 1
  • B. A. Tertov
    • 1
  1. 1.Rostov State UniversityRostov-on-Don

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