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α-Oxides in reaction with N-H acids of the heterocyclic series

IV. Alkylation of 1-methyl-3-nitro-1,2,4-triazol-5-one with olefin oxides

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Anumber of 1-methyl-4-(2-hydroxyalkyl)-3-nitro-1,2,4-triazol-5-ones and their derivatives were obtained by reaction of 1-methyl-3-nitro1,2,4-triazol-5-one with α-epoxides. The fact of intramolecular nucleophilic substitution of the nitro group in hydroxy derivatives of 3-nitro-1,2,4-triazol-5-one with cyclization to 2-methyl-3-oxo-5,6-dihydrooxazolo[3,2-b]-1,2,4-triazoline was established.

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Literature cited

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See [1] for communication III.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1407–1410, October, 1977.

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Kofman, T.P., Vasil'eva, I.V. & Pevzner, M.S. α-Oxides in reaction with N-H acids of the heterocyclic series. Chem Heterocycl Compd 13, 1129–1132 (1977). https://doi.org/10.1007/BF00480153

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  • DOI: https://doi.org/10.1007/BF00480153

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