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Imidazole derivatives

VII. Nitration of 4(5)-(4-alkoxyphenyl)imidazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is shown that 4(5)-(4-alkoxyphenyl)-5(4)-nitroimidazoles are obtained when 4(5)-(4-alkoxyphenyl)imidazoles are refluxed with 3–4 N nitric acid. The use of concentrated nitric acid (d 204 1.42, 1.46) leads to di- and trinitro-substituted phenylimidazoles. The mass spectra of the nitro derivatives were studied, and the principles of the fragmentation were ascertained.

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Deceased.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1384–1388, October, 1977.

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Iradyan, M.A., Torosyan, A.G., Mirzoyan, R.G. et al. Imidazole derivatives. Chem Heterocycl Compd 13, 1110–1113 (1977). https://doi.org/10.1007/BF00480148

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  • DOI: https://doi.org/10.1007/BF00480148

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