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Chemistry of Heterocyclic Compounds

, Volume 13, Issue 10, pp 1069–1072 | Cite as

Synthesis and study of the rate of aminolysis of O-(acylaminoacyl)oximes of formylpyridines and pyridyl methyl ketones

  • P. Ya. Romanovski
  • T. Plucinski
  • G. Kupryszewski
Article
  • 32 Downloads

Abstract

A number of O-(benzyloxycarbonylglycyl) derivatives of alkyl-, phenyl-, and pyridyl-substituted oximes were synthesized, and their chemical properties and reactivities under aminolysis conditions were studied. The principal factor that determines the reactivities of the investigated compounds during the formation of a peptide bond is the presence of a weakly acidic catalyst; the different reactivities of the compounds under the same conditions are due to the influence of the electron-acceptor effects of the substituents attached to the carbon atom of the oxime group.

Keywords

Peptide Methyl Organic Chemistry Phenyl Carbon Atom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • P. Ya. Romanovski
    • 1
    • 2
  • T. Plucinski
    • 1
    • 2
  • G. Kupryszewski
    • 1
    • 2
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga
  2. 2.Institute of ChemistryGdansk UniversityPoland

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