Chemistry of Heterocyclic Compounds

, Volume 13, Issue 10, pp 1065–1068 | Cite as

Derivatives of condensed systems based on pyrimidine, pyrazine, and pyridine

XXXVI. Synthesis of pyrimido[4,5-b]-1,4-thiazin-6-ones and pyrimido[4,5-b]-1,5-thiazepin-6-ones
  • A. F. Keremov
  • M. P. Nemeryuk
  • O. L. Aparnikova
  • T. S. Safonova


Pyrimido[4,5-b]-1,4-thiazin-6-one and pyrimido[4,5-b]-1,5-thiazepin-6-one derivatives were obtained by reaction of 5-amino-6-chloropyrimidines with thioglycolic acid and 5-amino-6-mercaptopyrimidines with β-bromopropionyl chloride. The IR spectra of the compounds are presented.


Chloride Organic Chemistry Pyridine Pyrimidine Pyrazine 
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Copyright information

© Plenum Publishing Corporation 1978

Authors and Affiliations

  • A. F. Keremov
    • 1
  • M. P. Nemeryuk
    • 1
  • O. L. Aparnikova
    • 1
  • T. S. Safonova
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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