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Synthesis of carbonyl derivatives of 3-phenylthiophene

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3-Phenyl-2-acetylthiophene was synthesized by the acetylation of 3-phenylthiophene with acetic anhydride in the presence of 56% perchloric acid. Previously undescribed α, β-unsaturated ketones were synthesized by the crotonic condensation of 3-phenyl-2-acetylthiophene with several aromatic and heterocyclic aldehydes.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1365–1367, October, 1971.

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Lipkin, A.E., Plakunov, V.M. Synthesis of carbonyl derivatives of 3-phenylthiophene. Chem Heterocycl Compd 7, 1276–1278 (1971). https://doi.org/10.1007/BF00479949

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  • DOI: https://doi.org/10.1007/BF00479949

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