Abstract
2-Methylthio-4-hydroxypyrimidines react with methylbromoacetate in methanol-sodium methoxide solution to give O- and N(3)-alkylated products, namely, 2-methylthio-4-(methoxycarbonyl)methoxypyrimidines and 2-methylthio-3-(methoxy-carbonyl)methylpyrimid-4-ones.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1520–1522, November, 1987.
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Vainilavichyus, P.I., Syadyaryavichyute, V.Y. Alkylation of 2-methylthio-4-hydroxypyrimidines by methyl bromoacetate. Chem Heterocycl Compd 23, 1216–1218 (1987). https://doi.org/10.1007/BF00479372
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DOI: https://doi.org/10.1007/BF00479372