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Synthesis and properties of oxazolo[3,2-f]xanthines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Oxazolo[3,2-f]xanthines were synthesized by the reaction of 7-acylalkyl-8-bromo-3-methyl- and -1,3-dimethylxanthines with sodium benzoate in dimethylformamide. Their alkylation with methyl iodine was studied. The reaction of oxazolo[3,2-f]xanthines with primary amines leads to the previously described imidazo[1,2-f]xanthines.

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Authors and Affiliations

  1. Zaporozhe Medical Institute, 330074, Zaporozhe

    S. N. Garmash, B. A. Priimenko, N. A. Klyuev, N. I. Romanenko, V. A. Golets & T. A. Kozik

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  1. S. N. Garmash
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  2. B. A. Priimenko
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  3. N. A. Klyuev
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  4. N. I. Romanenko
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  5. V. A. Golets
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  6. T. A. Kozik
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 534–537, April, 1988.

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Garmash, S.N., Priimenko, B.A., Klyuev, N.A. et al. Synthesis and properties of oxazolo[3,2-f]xanthines. Chem Heterocycl Compd 24, 442–445 (1988). https://doi.org/10.1007/BF00478866

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  • DOI: https://doi.org/10.1007/BF00478866

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