Abstract
The corresponding 4-arylmorpholine-2,3-diones were obtained by the reaction of N-(2-hydroxyethyl)aniline, N-(2-hydroxypropyl)aniline, N-(2-hydroxyethyl)-p-chloroaniline, and N-(2-hydroxyethyl)-p-anisidine with diethyl oxalate. The N-(2-hydroxyethyl)-o-, p-, and m-toluidines and N-(2-hydroxyethyl)-o-anisidine form 1,4-(ditolyl)piperazines and 1,4-di(o-anisyl)piperazine.
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U. S. Patent No. 2,723,247 (1955); Chem. Abstr., 50, 3011 (1956).
S. R. Tulyagonov, V. A. Saprykina, and M. R. Yagudaev, in: Biologically Active Compounds (a collection of articles from Zh. Org. Khim.) (1968), p. 19.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 22–24, January, 1971.
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Seitkasymov, Z., Tulyaganov, S.R. & Yunusov, A.I. Synthesis of 4-arylmorpholine -2,3-diones by the reaction of n-(2-hydroxyethyl)arylamines with diethyl oxalate. Chem Heterocycl Compd 7, 19–21 (1971). https://doi.org/10.1007/BF00477937
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DOI: https://doi.org/10.1007/BF00477937