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Functional derivatives of thiophene

VI. Synthesis, azo coupling, and aminomethylation of α-acylaminothiophenes

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A method was developed for the synthesis of 5-acylamino-2,3-dimethyl-and 5-acylamino-2,3-tetramethylenethiophenes by decarboxylation of the corresponding 5-acylaminothiophene-4-carboxylic acids. The azo coupling and aminomethylation of the synthesized acylaminothiophenes were studied.

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Literature cited

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Authors and Affiliations

  1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow

    V. I. Shvedov, I. A. Kharizomenova & A. N. Grinev

Authors
  1. V. I. Shvedov
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  2. I. A. Kharizomenova
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  3. A. N. Grinev
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Additional information

See [1] for communication V.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1624–1627, December, 1973.

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Shvedov, V.I., Kharizomenova, I.A. & Grinev, A.N. Functional derivatives of thiophene. Chem Heterocycl Compd 9, 1469–1472 (1973). https://doi.org/10.1007/BF00477559

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  • DOI: https://doi.org/10.1007/BF00477559

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