Chemistry of Heterocyclic Compounds

, Volume 8, Issue 4, pp 454–457 | Cite as

Indole derivatives

LXXVI. Synthesis of tris(1-benzyl-5-indolinyl)phosphine oxide and indole-5-phosphonic acid derivatives
  • V. P. Shamshin
  • V. F. Shner
  • N. N. Suvorov


Tris (1-benzyl-5-indolinyl)phosphine oxide, the structure of which was confirmed by alternative synthesis, is formed as a side product along with the previously described dimethyl-1-benzylindoline-5-phosphonate in the reaction of 1-benzyl-5-lithioindoline with dimethyl chlorophosphate. Dimethyl l-benzylindole-5-phosphonate was obtained by the dehydrogenation of dimethyl 1-benzylindoline-5-phosphonate with chloranil. The catalytic dehydrogenation of this same indollne is accompanied by debenzylation, which leads to dimethyl indole-5-phosphonate, and by splitting of the p-C bond.


Oxide Organic Chemistry Dimethyl Indole Dehydrogenation 
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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • V. P. Shamshin
    • 1
  • V. F. Shner
    • 1
  • N. N. Suvorov
    • 1
  1. 1.D. I. Mendeleev Moscow Chemical-Engineering InstituteUSSR

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