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Chemistry of Heterocyclic Compounds

, Volume 8, Issue 4, pp 454–457 | Cite as

Indole derivatives

LXXVI. Synthesis of tris(1-benzyl-5-indolinyl)phosphine oxide and indole-5-phosphonic acid derivatives
  • V. P. Shamshin
  • V. F. Shner
  • N. N. Suvorov
Article
  • 31 Downloads

Abstract

Tris (1-benzyl-5-indolinyl)phosphine oxide, the structure of which was confirmed by alternative synthesis, is formed as a side product along with the previously described dimethyl-1-benzylindoline-5-phosphonate in the reaction of 1-benzyl-5-lithioindoline with dimethyl chlorophosphate. Dimethyl l-benzylindole-5-phosphonate was obtained by the dehydrogenation of dimethyl 1-benzylindoline-5-phosphonate with chloranil. The catalytic dehydrogenation of this same indollne is accompanied by debenzylation, which leads to dimethyl indole-5-phosphonate, and by splitting of the p-C bond.

Keywords

Oxide Organic Chemistry Dimethyl Indole Dehydrogenation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • V. P. Shamshin
    • 1
  • V. F. Shner
    • 1
  • N. N. Suvorov
    • 1
  1. 1.D. I. Mendeleev Moscow Chemical-Engineering InstituteUSSR

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