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Chemistry of Heterocyclic Compounds

, Volume 8, Issue 4, pp 419–421 | Cite as

Dipole moments of some isoxazole derivatives

  • I. B. Mazheika
  • I. S. Yankovska
  • S. D. Sokolov
  • I. M. Yudintseva
Article

Abstract

The dipole moments of isoxazole and 13 of its halo, amino, and nitro derivatives were measured. A method is proposed for vector calculation for estimating the direction of the dipole moment of the isoxazole ring. It is demonstrated that phenyl substituents in the 3 and 5 positions are electron donors with respect to the isoxazole ring. It was found that the dipole moments of 4-substituted 3,5-dimethylisoxazoles correlate satisfactorily with the Hammett constants.

Keywords

Organic Chemistry Phenyl Dipole Moment Electron Donor Isoxazole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • I. B. Mazheika
    • 1
    • 2
  • I. S. Yankovska
    • 1
    • 2
  • S. D. Sokolov
    • 1
    • 2
  • I. M. Yudintseva
    • 1
    • 2
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga
  2. 2.S. Ordzhonikidze All-Union Scientific-Research Institute of Pharmaceutical ChemistryMoscow

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