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Synthesis in the phenothiazine series

XXIX. Imidazo[4,5,1-k,l]phenothiazine and its derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A new condensed system — imidazo[4,5,1-k,l]phenothiazine — was synthesized by the reaction of 1-aminophenothiazine with formic acid. The reaction of 1-aminophenothiazine with trifluoroacetic acid resulted in the formation of 1-trifluoromethylimidazo[4,5,1-k, l]phenothiazine. The cyclization of 1-acetamido- and 1-benzamidophenothiazines in the presence of hydrochloric acid gave 1-methyl- and 1-phenylimidazo[4,5,1-k, l]phenothiazines.

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Literature cited

  1. V. V. Shavyrina and S. V. Zhuravlev, Khim. Geterotsikl. Soedin., 42 (1971).

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Authors and Affiliations

  1. Institute of Pharmacology, Academy of Medical Sciences of the USSR, Moscow

    A. N. Gritsenko, Z. I. Ermakova, V. S. Troitskaya & S. V. Zhuravlev

Authors
  1. A. N. Gritsenko
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  2. Z. I. Ermakova
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  3. V. S. Troitskaya
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  4. S. V. Zhuravlev
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Additional information

See [1] for communication XXVIII.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 767–769, June, 1971.

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Gritsenko, A.N., Ermakova, Z.I., Troitskaya, V.S. et al. Synthesis in the phenothiazine series. Chem Heterocycl Compd 7, 715–717 (1971). https://doi.org/10.1007/BF00476815

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  • DOI: https://doi.org/10.1007/BF00476815

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