Abstract
The reaction of quaternized pyridin-3-ylidene malonitrile and cyanoacetate ester derivatives with 1,3-dicarbonyl compounds proceeds highly regioselectively to give substituted 2-amino-4-(1-methylpyridinium-3-yl)-4H-pyran iodides. The structure of 2-amino-3,5-dicarboethoxy-6-methyl-4-(1-methylpyridinium-3-yl)-4H-pyran iodide has been investigated by x-ray structural analysis.
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See [1] for communication No. 49.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 205–211, February, 1991.
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Shestopalov, A.M., Sharanin, Y.A., Khikuba, M.R. et al. Cyclization reactions of nitriles. 50. Regioselectivity in the reactions of quaternized pyridin-3-ylidene malonitrile and cyanoacetate ester derivatives with 1,3-dicarbonyl compounds. Crystal structure of 2-amino-3,5-dicarboethoxy-6-methyl-4-(1-methylpyridinium-3-yl)-4H-pyran iodide. Chem Heterocycl Compd 27, 166–172 (1991). https://doi.org/10.1007/BF00476751
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DOI: https://doi.org/10.1007/BF00476751