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Synthesis of pyrrolo[1,2-a]pyrimidine derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

8-Cyanopyrrolo[1,2-a]pyrimidines, the cyano group of which is eliminated when they are heated with phosphoric acid, were obtained by reaction of 2-amino-3-cyanopyrroles with acetylacetone.

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Literature cited

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Compounds Ia, c-g were described earlier in [3], while Ib, h are described in the present work.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1677–1681, December, 1976.

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Shvedov, V.I., Mezentseva, M.V., Grinev, A.N. et al. Synthesis of pyrrolo[1,2-a]pyrimidine derivatives. Chem Heterocycl Compd 12, 1379–1382 (1976). https://doi.org/10.1007/BF00476732

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  • DOI: https://doi.org/10.1007/BF00476732

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