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Research in the imidazole series

XCI. Hydrolysis of 7-cyano derivatives of pyrrolo[1,2-a]imidazole

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The hydrolysis of 7-cyano derivatives of pyrrolo[1,2-a]imidazole in 85–90% sulfuric acid at 100°C gives amides of pyrroloimidazole-7-carboxylic acids. Under more severe conditions, the resulting carboxylic acids are decarboxylated to the corresponding pyrroloimidazole derivatives with a free 7 position.

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Literature cited

  1. A. A. Druzhinina and P. M. Kochergin, Khim. Geterotsikl. Soedin., No. 11, 1552 (1976).

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  2. P. M. Kochergin, A. A. Druzhinina, and R. M. Palei, Khim. Geterotsikl. Soedin., No. 11, 1549 (1976).

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See [1] for communication XC.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1658–1659, December, 1976.

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Druzhinina, A.A., Kochergin, P.M. Research in the imidazole series. Chem Heterocycl Compd 12, 1363–1364 (1976). https://doi.org/10.1007/BF00476728

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  • DOI: https://doi.org/10.1007/BF00476728

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