Chemistry of Heterocyclic Compounds

, Volume 8, Issue 8, pp 986–987 | Cite as

Catalytic alkylation of pyridine and its homologs

II. Alkylation of 2-picoline with methanol in the presence of hydrogen chloride
  • V. N. Gudz'
  • S. A. Trifonova
  • A. N. Shpagina


In the reaction of 2-picoline with methanol in the presence of hydrogen chloride, alkylation proceeds primarily at the side methyl group to form 2-ethyl- and 2-isopropylpyridines, together with small amounts of 3-picoline and 2,3- and 2,6-lutidines.


Hydrogen Methyl Chloride Methanol Organic Chemistry 
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Literature cited

  1. 1.
    V. N. Gudz' and A. D. Dartsev, Khim. Geterotsikl. Soedin., 271 (1968).Google Scholar
  2. 2.
    V. N. Gudz', A. D. Dartsev, and S. A. Trifonova, USSR Author's Certificate No. 196,842 (1967); Byull. Izobr., No. 12 (1967).Google Scholar
  3. 3.
    L. I. Vereshchagin and I. L. Kotlyarevskii, Usp. Khim., 30, 985 (1961).Google Scholar
  4. 4.
    G. A. Collins, British Patent No. 850,405 (1960); Ref. Zh. Khim., 14L180 (1961).Google Scholar
  5. 5.
    N. S. Kozlov and N. I. Panova, Zh. Obshch. Khim., 25, 183 (1955).Google Scholar

Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • V. N. Gudz'
    • 1
  • S. A. Trifonova
    • 1
  • A. N. Shpagina
    • 1
  1. 1.Buryatskii Institute of Natural SciencesBuryatskii Agricultural InstituteUlan-Udé

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