Chemistry of Heterocyclic Compounds

, Volume 8, Issue 8, pp 974–977 | Cite as

Methyl γ-phenylacetate in the Fischer indole synthesis

  • V. I. Shvedov
  • G. N. Kurilo
  • A. N. Grinev


Nitrogen-substituted methyl γ-phenyl-β-hydrazinocrotonates form methyl 3-phenyl-2-indolylacetates or methyl 2-benzylindole-3-carboxylates in acid media. The latter react with polyphosphoric acid to give benzo[b]carbazole derivatives, from which the corresponding 6,11-dioxobenzo[b]carbazoles are obtained by oxidation.


Oxidation Methyl Organic Chemistry Indole Acid Medium 
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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • V. I. Shvedov
    • 1
  • G. N. Kurilo
    • 1
  • A. N. Grinev
    • 1
  1. 1.S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry InstituteMoscow

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