Advertisement

Chemistry of Heterocyclic Compounds

, Volume 8, Issue 8, pp 939–942 | Cite as

Synthesis of substituted 2-amino-5,6-dihydro-4h-1, 3-oxazines

  • L. A. Ignatova
  • P. L. Ovechkin
  • M. Z. Branzburg
  • A. E. Gekhman
  • B. V. Unkovskii
Article
  • 45 Downloads

Abstract

4,4,6-Trimethyl-2-alkyl(aryl)amino-5,6-dihydro-4H-1,3-oxazines were synthesized via two methods: amination of 4,4,6-trimetiiyl-2-methylthio-5,6-dihydro-4H-1,3-oxazine and cyclization of N-aryl-N′-(2-methyl-4-hydroxy-2-amyl)-S-methylisothiourea.

Keywords

Organic Chemistry Oxazine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature cited

  1. 1.
    B. V. Unkovskii, L. A. Ignatova, P. L. Ovechkin, and A. I. Vinogradova, Khim. Geterotsikl. Soedin., 1090 (1970).Google Scholar
  2. 2.
    P. L. Ovechkin, L. A. Ignatova, and B. V. Unkovskii, Khim. Geterotsikl. Soedin., 946 (1971).Google Scholar
  3. 3.
    S. Gabriel and W. Lauer, Ber., 23, 95 (1890).Google Scholar
  4. 4.
    D. Pearson and M. Sigal, J. Org. Chem., 15, 1055 (1950).Google Scholar
  5. 5.
    H. Nayer, J. Armand, J. Menin, and N. Voronin, Compt. Rend., 260, 4343 (1965).Google Scholar
  6. 6.
    R. Clapp, F. Bissett, and L. Long, J. Heterocycl. Chem., 5, 107 (1968).Google Scholar
  7. 7.
    J. Meschino and C. Bond, J. Org. Chem., 28, 3129 (1963).Google Scholar
  8. 8.
    G. Kjellin and J. Sandström, Acta Chem. Scand., 23, 2888 (1969).Google Scholar
  9. 9.
    R. Jones and A. Katritzky, J. Chem. Soc., 3611 (1958).Google Scholar
  10. 10.
    A. Albert and G. Barlin, J. Chem. Soc., 2384 (1959).Google Scholar
  11. 11.
    R. Mecke, R. Mecke, and A. Lüttringhaus, Ber., 90, 975 (1957).Google Scholar
  12. 12.
    K. Jensen and H. Nielsen, Acta Chem. Scand., 20, 597 (1966).Google Scholar
  13. 13.
    A. Rosen, J. Am. Chem. Soc., 74, 2994 (1952).Google Scholar
  14. 14.
    M. Kohn, Monatsh., 25, 817 (1904).Google Scholar

Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • L. A. Ignatova
    • 1
  • P. L. Ovechkin
    • 1
  • M. Z. Branzburg
    • 1
  • A. E. Gekhman
    • 1
  • B. V. Unkovskii
    • 1
  1. 1.M. V. Lomonosov Moscow Institute of Precision Chemical EngineeringUSSR

Personalised recommendations