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Chemistry of Heterocyclic Compounds

, Volume 9, Issue 1, pp 31–33 | Cite as

Indoles

XXXV. Ratio of 4-nitro- and 6-nitroindoles formed in the Fischer cyclization of m-nitrophenylhydrazones
  • I. I. Grandberg
  • L. D. Belyaeva
  • L. B. Dmitriev
Article

Abstract

The cyclization of diethyl ketone m-nitrophenylhydrazone under different conditions always gives a mixture of the isomeric 4-nitro-3-methyl-2-ethylindole and 6-nitro-3-methyl-2-ethylindole, generally with a certain predominance of the former. The isomer ratio depends on the nature of the catalyst used. Only 6-nitro-2,3,3-trimethylindolenine is formed in the cyclization of methyl isopropyl ketone m-nitrophenylhydrazone.

Keywords

Methyl Organic Chemistry Ketone Diethyl Indole 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1975

Authors and Affiliations

  • I. I. Grandberg
    • 1
  • L. D. Belyaeva
    • 1
  • L. B. Dmitriev
    • 1
  1. 1.K. A. Timiryazev Moscow Agricultural AcademyUSSR

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