The alkylation of 3-isoxazolidone and its metal salts with diazomethane and alkyl halides was investigated for the first time. The alkylation products are a mixture of two isomers — derivatives of the lactam and lactim forms of 3-isoxazolidone. The major component in all cases is the N-alkylation product. The percentage of isomeric imino ethers depends on the nature and structure of the reagents.
KeywordsEther Organic Chemistry Alkylation Halide Metal Salt
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