Abstract
The alkylation of 3-isoxazolidone and its metal salts with diazomethane and alkyl halides was investigated for the first time. The alkylation products are a mixture of two isomers — derivatives of the lactam and lactim forms of 3-isoxazolidone. The major component in all cases is the N-alkylation product. The percentage of isomeric imino ethers depends on the nature and structure of the reagents.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 3–7, January, 1973.
The authors thank I. V. Dipan and S. P. Yurel' for recording the IR spectra and gas-liquid chromatograms.
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Voitenko, A.D., Kastron, Y.A., Liepin', É.É. et al. Alkylation of 3-isoxazolidone. Chem Heterocycl Compd 9, 1–5 (1973). https://doi.org/10.1007/BF00476136
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DOI: https://doi.org/10.1007/BF00476136