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Chemistry of Heterocyclic Compounds

, Volume 9, Issue 1, pp 1–5 | Cite as

Alkylation of 3-isoxazolidone

  • A. D. Voitenko
  • Ya. A. Kastron
  • É. É. Liepin'
  • S. A. Giller
Article

Abstract

The alkylation of 3-isoxazolidone and its metal salts with diazomethane and alkyl halides was investigated for the first time. The alkylation products are a mixture of two isomers — derivatives of the lactam and lactim forms of 3-isoxazolidone. The major component in all cases is the N-alkylation product. The percentage of isomeric imino ethers depends on the nature and structure of the reagents.

Keywords

Ether Organic Chemistry Alkylation Halide Metal Salt 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    N. I. Kochetkov, R. M. Khomutov, E. S. Severin, M. Ya. Karpeiskii, É. I. Budovskii, and V. I. Erashko, Zh. Obshch. Khim., 29, 3417 (1959).Google Scholar
  2. 2.
    V. G. Vinokurov, V. S. Troitskaya, and N. K. Kochetkov, Zh. Obshch. Khim., 31, 205 (1961).Google Scholar
  3. 3.
    C. H. Shunk, F. W. Bachelor, and K. Folkers, J. Org. Chem., 22, 76 (1957).Google Scholar
  4. 4.
    A. J. Durbetaki, Anal. Chem., 28, 2000 (1956).Google Scholar

Copyright information

© Consultants Bureau, a division of Plenum Publishing Corporation 1975

Authors and Affiliations

  • A. D. Voitenko
    • 1
  • Ya. A. Kastron
    • 1
  • É. É. Liepin'
    • 1
  • S. A. Giller
    • 1
  1. 1.Institute of Organic SynthesisAcademy of Sciences of the Latvian SSRRiga

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