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Reaction of hydroxy derivatives of piperidines and pyridines with acetylene under pressure

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Methods for the synthesis of vinyl ethers of N-(β-hydroxyethyl)-piperidine, 3-hydroxy-N-methylpiperidine, 2-(β-hydroxyethyl)pyridine, and 2-(hydroxypyridine) based on the addition of the corresponding derivatives to acetylene have been developed. Their hydrogenation forms the corresponding ethyl ethers.

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Shostakovskii, M.F., Skvortsova, G.G., Tyrina, S.M. et al. Reaction of hydroxy derivatives of piperidines and pyridines with acetylene under pressure. Chem Heterocycl Compd 5, 759–761 (1972). https://doi.org/10.1007/BF00475849

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  • DOI: https://doi.org/10.1007/BF00475849

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