Abstract
Methods for the synthesis of vinyl ethers of N-(β-hydroxyethyl)-piperidine, 3-hydroxy-N-methylpiperidine, 2-(β-hydroxyethyl)pyridine, and 2-(hydroxypyridine) based on the addition of the corresponding derivatives to acetylene have been developed. Their hydrogenation forms the corresponding ethyl ethers.
Similar content being viewed by others
References
Y. B. Butler and R. L. Yoette, J. Am. Chem. Soc., 74, 39, 1952.
S. R. Sergienko, Yu. A. Bedov, and L. V. Ratnikova, DAN, 102, 101, 1955.
B. M. Kuindzhi, L. D. Gluzman, M. A. Zepalova, R. M. Tsip, A. K. Val'kova, and A. A. Rok, USSR patent no. 135488, 1961; Byull. izobr., no. 3, 1961.
W. H. Watanabe, and L. E. Conlon, J. Am. Chem. Soc., 79, 28, 1957.
E. S. Levin and G. N. Rodionova, DAN, 164, 584, 1965.
L. Hunter, J. Chem. Soc., 806, 945; 2857, 1950.
Yu. N. Sheinker and V. M. Resnikov, DAN, 102, 109, 1955.
B. I. Mikhant'ev and E. I. Fedorov, Izvestiya VUZ. Khimiya, 2, 390, 1959.
T. Takahashi and M. Kawashima, J. Pharm. Soc. Japan. 63, 546, 1943.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Shostakovskii, M.F., Skvortsova, G.G., Tyrina, S.M. et al. Reaction of hydroxy derivatives of piperidines and pyridines with acetylene under pressure. Chem Heterocycl Compd 5, 759–761 (1972). https://doi.org/10.1007/BF00475849
Issue Date:
DOI: https://doi.org/10.1007/BF00475849