Abstract
In the Fischer cyclization of the 3-(2′-bromo-5′-phenylhydrazone) of piperidine-2,3-dione, two isomeric carbolines were isolated-8-bromo-5-methoxy-1-oxo-1,2,3,4-tetrahydro-β-carboline and 6-bromo-7-methoxy-1-oxo-1,2,3,4-tetrahydro-β-carboline. The formation of the latter shows that cyclization is accompanied by the migration of the bromine.
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Morozovskaya, L.M., Ogareva, O.B. & Suvorov, N.N. Indole derivatives. Chem Heterocycl Compd 5, 749–751 (1972). https://doi.org/10.1007/BF00475846
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DOI: https://doi.org/10.1007/BF00475846