Chemistry of Heterocyclic Compounds

, Volume 8, Issue 10, pp 1237–1241 | Cite as

Chemistry of indole

XXXII. Reaction of 1-methyl-2-aminoindole with aldehydes
  • A. N. Kost
  • R. S. Sagitullin
  • T. V. Mel'nikova
  • G. V. Kaplun


The condensation of salts of 1-methyl-2-aminoindole with aldehydes in excess alkali gives Schiff bases, while salts of 1-methyl-3-arylidene-2-iminoindolines are obtained in the absence of alkali. The latter may give 12-aryl-5,7-dimethylindolo[2,3-b]-α-carbolines (I) on reaction with excess 1-methyl-2-aminoindole. Dihydro compounds (II) are formed as intermediates.


Organic Chemistry Aldehyde Indole Schiff Base Schiff 
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Copyright information

© Consultants Bureau 1974

Authors and Affiliations

  • A. N. Kost
    • 1
  • R. S. Sagitullin
    • 1
  • T. V. Mel'nikova
    • 1
  • G. V. Kaplun
    • 1
  1. 1.M. V. Lomonosov Moscow State UniversityUSSR

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