Abstract
A new synthesis of 5-azaindole and its derivatives has been developed, which consists in the reaction of 6-oxo-2, 3-dihydro-5-azabenzofuran with primary amines, followed by elimination of the substituent in the 6-position and dehydrogenation of the resulting 5-azaindolines with a palladium catalyst. Electrophilic substitution reactions in the 6-oxo-5-azaindoles are investigated.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
L. N. Yakhontov and M. S. Sokolova, KhGS [Chemistry of Heterocyclic Compounds], 1111, 1969.
L. N. Yakhontov, M. Ya. Uritskaya, and M. V. Rubtsov, KhGS [Chemistry of Heterocyclic Compounds], 918, 1965.
L. N. Yakhontov, E. I. Lapan, and M. V. Rubtsov, KhGS [Chemistry of Heterocyclic Compounds], 550, 1969.
L. N. Yakhontov, E. I. Lapan, M. Ya. Uritskaya, D. M. Krasnokutskaya, G. P. Zhikhareva, and M. V. Rubtsov, USSR patent no. 202956, 1967; Byull. izobr., no. 20, 39, 1967.
L. N. Yakhontov, M. Ya. Uritskaya, E. I. Lapan, and M. V. Rubtsov, KhGS [Chemistry of Heterocyclic Compounds], 18, 1968.
L. N. Yakhontov, M. Ya. Uritskaya, V. A. Loginova, and M. V. Rubtsov, KhGS [Chemistry of Heterocyclic Compounds], 456, 1969.
N. N. Koretskaya, K. A. Chkhikvadze, N. S. Rodnyanskaya, and O. Yu. Magidson, Khim.-farm. zhurn., no. 6, 5, 1968.
L. N. Yakhontov and M. V. Rubtsov, ZhOKh, 34, 493, 1964.
L. N. Yakhontov, M. Ya. Uritskaya, and M. V. Rubtsov, ZhOKh, 34, 1449, 1964.
N. N. Suvorov and M. N. Preobrazhenskaya, ZhOKh, 31, 2839, 1961.
A. P. Terent'ev and M. N. Preobrazhenskaya, DAN, 121, 481, 1958.
Author information
Authors and Affiliations
Additional information
For part XXIX, see [1]
Rights and permissions
About this article
Cite this article
Yakhontov, L.N., Lapan, E.I. Azaindole derivatives. Chem Heterocycl Compd 6, 23–27 (1970). https://doi.org/10.1007/BF00475417
Issue Date:
DOI: https://doi.org/10.1007/BF00475417