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Synthesis of aromatic pyrazolo[4,5-b]pyridine derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Cyclocondensation of chalcones with 5-amino-3-methyl-1-phenylpyrazole leads to the formation of 2,4-diaryl-5-methyl-7-phenyl-3,4-dihydropyrazolo-[4,5-b]pyridines, which undergo aromatization upon treatment with N-bromosuccinimide.

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Literature Cited

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1247–1251, September, 1987.

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Orlov, V.D., Kiroga, K. & Kolos, N.N. Synthesis of aromatic pyrazolo[4,5-b]pyridine derivatives. Chem Heterocycl Compd 23, 997–1001 (1987). https://doi.org/10.1007/BF00475369

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  • DOI: https://doi.org/10.1007/BF00475369

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