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Synthesis, properties, and X-ray diffraction study of 4-trifluoromethyl-6-phenyl-2-chloro-3-cyanopyridine

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

4-Trifluoromethyl-6-phenyl-2-chloro-3-cyanopyridine was synthesized, and its molecular-crystal structure was established. The chlorine atom was replaced by amino, mercapto, thiocyanato, and azido groups. The possibility of the direct amination of 4-trifluoromethyl-6-phenyl-3-cyano-2-pyridone by the action of hexamethylphosphoric triamide (HMPT) was demonstrated.

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Literature Cited

  1. Z. A. Bomika, M. B. Andaburskaya, Yu. é. Pelcher, and G. Ya. Dubur, Khim. Geterotsikl. Soedin., No. 8, 1085 (1976).

    Google Scholar 

  2. P. Nantka-Namirski and L. Kaczmarek, Acta Pol. Pharm., 35, 393 (1978).

    Google Scholar 

  3. R. Balicki and P. Nantka-Namirski, Pol. J. Chem., 53, 1515 (1979).

    Google Scholar 

  4. é. Yu. Gudrinietse, A. V. Suttsait, and S. V. Belyakov, Izv. Akad. Nauk Latv. SSR, Ser. Khim., No. 5, 611 (1984).

    Google Scholar 

  5. S. Portnoy, J. Heterocycl. Chem., 6, 223 (1969).

    Google Scholar 

  6. E. Schroetter, H. Schick, H. Niedrich, P. Ochme, and L. Piesche, East German Patent No. 154,537; Chem. Abstr., 98, 53697 (1983).

    Google Scholar 

  7. W. R. Busing and H. A. Levy, Acta Crystalogr., 17, 142 (1964).

    Google Scholar 

  8. é. A. Arutyunyan, V. I. Gunar, V. P. Gracheva, and S. I. Zav'yalov, Izv. Akad. Nauk SSSR, Ser. Khim., 3, 655 (1969).

    Google Scholar 

  9. L. A. Rodinovskaya, Yu. A. Sharanin, V. P. Litvinov, A. M. Shestopalov, V. K. Promonenkov, B. M. Zolotarev, and V. Yu. Mortikov, Zh. Org. Khim., No. 11, 2439 (1985).

    Google Scholar 

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Authors and Affiliations

  1. A. Ya. Pel'she Riga Polytechnical Institute, 226048, Riga

    A. V. Guttsait, S. V. Belyakov, A. F. Mishnev, Ya. Ya. Bleidelis & é. Yu. Gudrinietse

  2. Institute of Organic Synthesis, Academy of Siences of the Latvian SSR, 226006, Riga

    A. V. Guttsait, S. V. Belyakov, A. F. Mishnev, Ya. Ya. Bleidelis & é. Yu. Gudrinietse

Authors
  1. A. V. Guttsait
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  2. S. V. Belyakov
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  3. A. F. Mishnev
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  4. Ya. Ya. Bleidelis
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  5. é. Yu. Gudrinietse
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1233–1237, September, 1987.

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Guttsait, A.V., Belyakov, S.V., Mishnev, A.F. et al. Synthesis, properties, and X-ray diffraction study of 4-trifluoromethyl-6-phenyl-2-chloro-3-cyanopyridine. Chem Heterocycl Compd 23, 986–989 (1987). https://doi.org/10.1007/BF00475366

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  • DOI: https://doi.org/10.1007/BF00475366

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