Abstract
Heating 2-methoxytetrahydrofuran with ethylmagnesium bromide in benzene at reflux leads to the formation of 2-ethoxytetrahydrofuran and slight amounts of 4-methoxy-1-hexanol. Under analogous conditions, 2-ethoxytetrahydrofuran is quantitatively cleaved by methylmagnesium iodide to give 4-ethoxy-1-pentanol.
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For Communication 1, see [1]
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 592–594, May, 1992.
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Polivin, Y.N., Trofimova, M.V., Karakhanov, R.A. et al. Synthesis and properties of furan derivatives 2. Role of the halogen in RMgX in reactions with alkoxytetrahydrofurans. Chem Heterocycl Compd 28, 494–496 (1992). https://doi.org/10.1007/BF00475242
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DOI: https://doi.org/10.1007/BF00475242