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Carbolines

I. 1, 4-disubstituted Β-carbolines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

4-Substituted 3, 4-dihydro-Β-carbolines (X–XVI) were obtained by the Beckman rearrangement of oximes of Β-(indolyl-3′)ketones (I–IV, IX) under the action of phosphorus pentachloride in nitrobenzene. 3, 4-Dihydro-Β-carbolines were converted into Β-carbolines (XV–XVII) on heating with Brown's palladium catalyst in ethylene glycol. Oximes containing the aryl group react on treatment with p-toluene sulfochloride in pyridine with the formation of the arilides of Β-(indolyl-3′)propionic acids.

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Authors and Affiliations

  1. Institute of Chemistry AS Moldavian SSR, Kishinev

    K. I. Kuchkova, A. A. Semenov & I. V. Terent'eva

Authors
  1. K. I. Kuchkova
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  2. A. A. Semenov
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  3. I. V. Terent'eva
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Additional information

For preliminary report, see [18].

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Kuchkova, K.I., Semenov, A.A. & Terent'eva, I.V. Carbolines. Chem Heterocycl Compd 6, 182–186 (1970). https://doi.org/10.1007/BF00474993

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  • DOI: https://doi.org/10.1007/BF00474993

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