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Synthesis of halogen substituted imidazo[4,5-e][1,4]diazepine-5,8-diones. Cyclic homologs of methylxanthines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Possible routes for synthesis of 2-haloimidazo[4,5-e][1,4]diazepines are discussed. Conditions for chlorination differ for homologs of caffeine, theophylline, and theobromine. For the caffeine homolog, both the 2-chloroand 2,6,6-trichloro products are obtained depending on the synthetic conditions

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References

  1. R. F. Elderfield (ed.), Heterocyclic Compounds [Russian translation], Vol. 8, Mir, Moscow (1969), p. 214.

    Google Scholar 

  2. É. I. Ivanov, A. V. Bogatskii, and K. S. Zakharov, Dokl. Akad. Nauk, 255, 591 (1980).

    Google Scholar 

  3. R. F. Elderfield (ed.), Heterocyclic Compounds [Russian translation], Vol. 8, Mir, Moscow (1969), p. 234.

    Google Scholar 

  4. D. Barton and W. D. Ollis, General Organic Chemistry [Russian translation], Vol. 3, Khimiya, Moscow (1982), p. 577.

    Google Scholar 

  5. D. Barton and W. D. Ollis, General Organic Chemistry [Russian translation], Vol. 8, Khimiya, Moscow (1982), p. 623.

    Google Scholar 

  6. A. V. Bogatskii and É. I. Ivanov, Ukr. Khim. Zh., No. 10, 1074 (1980).

    Google Scholar 

  7. É. I. Ivanov, I. M. Yaroshchenko, and G. D. Kalayanov, Ukr. Khim. Zh., No. 12, 1316 (1990).

    Google Scholar 

  8. G. Brauer (ed.), Handbook of Inorganic Synthesis [Russian Translation], Vol. 2, Mir, Moscow (1985), p. 355.

    Google Scholar 

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Authors and Affiliations

  1. A. V. Bogatskii Physicochemical Institute, Ukrainian Academy of Sciences, 270080, Odessa

    É. I. Ivanov, G. D. Kalayanov & I. M. Yaroshchenko

Authors
  1. É. I. Ivanov
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  2. G. D. Kalayanov
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  3. I. M. Yaroshchenko
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 955–958, July, 1992.

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Ivanov, É.I., Kalayanov, G.D. & Yaroshchenko, I.M. Synthesis of halogen substituted imidazo[4,5-e][1,4]diazepine-5,8-diones. Cyclic homologs of methylxanthines. Chem Heterocycl Compd 28, 795–797 (1992). https://doi.org/10.1007/BF00474495

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  • DOI: https://doi.org/10.1007/BF00474495

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